This search combines search strings from the content search (i.e. "Full Text", "Author", "Title", "Abstract", or "Keywords") with "Article Type" and "Publication Date Range" using the AND operator.
Beilstein J. Org. Chem. 2012, 8, 514–521, doi:10.3762/bjoc.8.58
Graphical Abstract
Figure 1: Structure of trehalose (1), validoxylamine A (2), 1-thiatrehazolin (3), trehalostatin (4), casuarin...
Figure 2: Structure of nojirimycin-based (7, 8) and pyrrolidine-based (9) leads.
Figure 3: Structures of potential inhibitors 10–21.
Scheme 1: Synthesis of nojirimycin-based inhibitors 10,12 and 13. Reagents and conditions: (a) H2, Pd/C, NH4O...
Scheme 2: Synthesis of pyrrolidine derivatives 14, 16, 17 and 19. Reagents and conditions: (a) H2, Pd(OH)2/C,...
Scheme 3: Synthesis of pyrrolidines 20 and 21. Reagents and conditions: (a) H2, Pd/C, MeOH, HCl; (b) octanal,...
Figure 4: Histogram of the inhibitory activity of compounds 7–10, 12–14, 16 and 20. Derivatives 10, 14 and 16...